Surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy are the main treatments for tumors. The adverse reactions caused by treatment cannot be ignored. Many adverse reactions are clinically fatal, so recognize them early, grade them according to their severity, and treat them as early as possible. The overall survival of cancer patients has been significantly improved.

The current classification of adverse reactions mainly refers to the fourth edition of CTCAE, which is divided into 5 levels:

Grade 1: Mild; asymptomatic or mild symptoms; only clinical or diagnostic findings; no treatment required.

Grade 2: Moderate; minor, local, or noninvasive treatment required; age-appropriate limitations in instrumental activities of daily living.

Grade 3: Serious or medically important but not immediately life-threatening; resulting in hospitalization or prolonged hospitalization; disability; limitation of independent activities of daily living.

Level 4: Life-threatening; emergency treatment required.

Level 5: Death related to AE.

Activities of Daily Living (ADL):

➤Instrumental activities of daily living include cooking, buying groceries or clothing, using the phone, managing money, etc.

➤Autonomous activities of daily living refer to washing, dressing and undressing, eating, going to the toilet, taking medicine, etc., and not being bedridden.

nervous system

Breathing, chest or mediastinum

digestive system

urinary system

blood and lymphatic system

Systemic

immune system

Musculoskeletal and connective tissue

Skin and subcutaneous tissue

infection and contagion

laboratory tests

references:

[1] U.S. Department of Health and Human Services. Common Adverse Reaction Time Evaluation Criteria Version 4.0

[2] Shi Yuankai, Sun Yan. Handbook of Clinical Oncology (Sixth Edition). [M]. People's Medical Publishing House. 2016: Appendix 1-6.